What was the longest-running prime-time TV game show? August 5, 2020November 8, 2011 by Pamela Landy “What’s My Line?” was the longest-running prime-time TV game show. It ran seventeen years from 1950 to 1967 on CBS. Related AnswersWhat was Broadway's all-time longest-running show? Broadway's all-time longest-running show was A Chorus Line. It ran…When was the "Top Cat" series on prime-time TV? In the 1961-62 season, the "Top Cat" series was on…What was the first prime-time soap opera? Appearing long before "Peyton Place" (ABC, 1964-69), the first prime-time…What is the longest-running national television series? NBC's "Meet the Press" has been running since November 20,…What was the longest-running sitcom on TV? "The Adventures of Ozzie and Harriet," which ran for fourteen…What is the longest-running daytime TV drama? "Search for Tomorrow" (CBS, 1951-1982; NBC 1982-1987) was the longest-running…